Artículos de revistas
Determination of atenolol in environmental water samples and pharmaceutical formulations at a graphite-epoxy composite electrode
Fecha
2012Registro en:
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, ABINGDON, v. 92, n. 5, supl. 1, Part 6, pp. 561-570, SEP, 2012
0306-7319
10.1080/03067310903582358
Autor
Calixto, Carolina Maria Fioramonti
Assumpção, Priscila Cervini
Cavalheiro, Eder Tadeu Gomes
Institución
Resumen
A bare graphite-epoxy composite was evaluated as an electrode material in the determination of atenolol in natural water samples and pharmaceutical formulations for which the analyte was spiked. Using a DPV procedure, a linear response was observed in the 4.45-84.7 mu mol L-1 range with a LOD = 2.23 mu mol L-1, without need of surface renewal between successive runs, and recoveries between 92.5 and 107.5% for pharmaceutical formulations. The results obtained from the proposed procedure agreed with HPLC results within a 95% confidence level. During the determination of atenolol in water samples, recoveries between 96.1 and 102.6% were found.