Artículos de revistas
Gene expression of peripheral blood lymphocytes may discriminate patients with schizophrenia from controls
Fecha
2012Registro en:
PSYCHIATRY RESEARCH, CLARE, v. 200, n. 2-3, pp. 1018-1021, DEC 30, 2012
0165-1781
10.1016/j.psychres.2012.04.030
Autor
Maschietto, Mariana
Silva, Aderbal R.
Puga, Renato D.
Lima, Leandro
Pereira, Carlos B.
Nakano, Eduardo Y.
Mello, Barbara
Gama, Clarissa S.
Belmonte-de-Abreu, Paulo
Carraro, Dirce M.
Palha, Joana A.
Brentani, Helena
Institución
Resumen
To identify a classifier in schizophrenia, blood gene expression profiling was applied to patients with schizophrenia under different treatments and to controls. Expression of six genes discriminated patients with sensitivity of 89.3% and specificity of 90%, supporting the use of peripheral blood as biological material for diagnosis in schizophrenia. (C) 2012 Elsevier Ireland Ltd. All rights reserved.