Artículos de revistas
Relapse of Intravenous Drug Use Triggered by Enfuvirtide, a Parenteral Antiretroviral Medication
Fecha
2012Registro en:
AIDS PATIENT CARE AND STDS, NEW ROCHELLE, v. 26, n. 2, supl. 4, Part 1, pp. 71-72, FEB, 2012
1087-2914
10.1089/apc.2011.0343
Autor
Avelino-Silva, Vivian Iida
Gallafrio Novaes, Christina Terra
Institución
Resumen
Fuzeon (R) (enfuvirtide; Hoffmann-LaRoche, Nutley, NJ) is a parenteral medication prescribed to antiretroviral-experienced HIV patients. Clinicians are frequently concerned when prescribing enfuvirtide to former drug addicts because of the risk of triggering relapse, however, no previous report has described this adverse event. We describe two HIV-infected patients, previously abstinent from injection drug use, who experienced relapse or near-relapse situations after starting treatment with enfuvirtide. Along with the concerns related to adherence and to injection site reactions, clinicians who prescribe enfuvirtide should consider and discuss the risk of triggering relapse among former or recovering drug addicts.