Artículos de revistas
Synthesis and application of chiral beta-amino disulfides as ligands for the enantioselective addition of diethylzinc to aldehydes
Fecha
2008Registro en:
CHIRALITY, v.20, n.7, p.839-845, 2008
0899-0042
10.1002/chir.20554
Autor
BRAGA, Antonio L.
GALETTO, Fabio Z.
RODRIGUES, Oscar E. D.
SILVEIRA, Claudio C.
PAIXAO, Marcio W.
Institución
Resumen
A new class of chiral beta-amino disulfides was synthesized from readily available and inexpensive starting materials by a straightforward method and their abilities as ligands were examined in the enantioselective addition of diethylzinc to aldehydes. Enantiomeric excesses of up to 99% have been obtained using 0.5 mol % of the chiral catalysts.