Artículos de revistas
SYNTHESIS AND RETRO AZA DIELS-ALDER REACTION OF SOME NEW ISOQUINUCLIDINE DERIVATIVES
Fecha
2009Registro en:
HETEROCYCLES, v.78, n.5, p.1223-1233, 2009
0385-5414
10.3987/COM-08-11610
Autor
MARZORATI, Liliana
VITTA, Patricia Busko Di
WLADISLAW, Blanka
SCHPECTOR, Julio Zukerman
VITTA, Claudio Di
Institución
Resumen
N-Benzyl- and N-(alpha-methoxycarbonylethyl)-2,4,6-triphenyl-1,2-dihydropyridines were submitted to Diels-Alder reactions with maleic anhydride or N-phenylmaleimide yielding, diastereoselectively, the corresponding endo-anti adducts. These novel isoquinuclidines showed to be resistant to N-alkylation or N-protonation, undergoing an unexpected fragmentation via a retro aza Diels-Alder process.