Artículos de revistas
Optimization of the ultrasound-assisted synthesis of allyl 1-naphthyl ether using response surface methodology
Fecha
2011Registro en:
ULTRASONICS SONOCHEMISTRY, v.18, n.2, p.489-493, 2011
1350-4177
10.1016/j.ultsonch.2010.10.003
Autor
FERNANDES, Joao Paulo dos Santos
CARVALHO, Bruno Simoes
LUCHEZ, Cibele Venancio
POLITI, Mario Jose
BRANDT, Carlos Alberto
Institución
Resumen
Allyl 1-naphthyl ethers are useful compounds for different purposes, but reported methods to synthesize them require long reaction times. In this work, we have obtained allyl 1-naphthyl ether in good yield using ultrasonic-assisted methodology in a 1-h reaction. A central composite design was used to obtain a statistical model and a response surface (p < 0.05; R(2) = 0.970; R(adj)(2) = 0.949; R(pred)(2) = 0.818) that can predict the optimal conditions to maximize the yield, validated experimentally. (C) 2010 Elsevier B.V. All rights reserved.