Artículos de revistas
Genetic typing of Trypanosoma cruzi isolates from different hosts and geographical areas of western Venezuela
Fecha
2009Registro en:
BOLETIN DE MALARIOLOGIA Y SALUD AMBIENTAL, v.49, n.2, p.251-258, 2009
1690-4648
Autor
ANEZ, Nestor
CRISANTE, Gladys
ANEZ-ROJAS, Nestor
ROJAS, Agustina
MORENO, Glenda
SILVA, Flavia Maia da
TEIXEIRA, Marta M. G.
Institución
Resumen
A total of 72 Trypanosoma cruzi isolates from different hosts and geographical regions of western Venezuela, where Chagas disease is endemic, were typed using ribosomal and mini-exon gene markers. The isolates were obtained from wild, peridomestic and domestic sources including triatomine-bugs, human acute chagasic patients and other mammals. Results showed that T. cruzi two major phylogenetic lineages, T. cruzi I and T. cruzi II were present. However, a remarkable predominance of T. cruzi I (96%) over T. cruzi II (4%) was observed. The present results suggest that in western Venezuela circulation of both T. cruzi I and T. cruzi II isolates is independent from the source of isolation and the geographical area where they occur, with predominance of T. cruzi I. The epidemiological significance of the present results is discussed.