Artículos de revistas
Transcriptional Processing of the pst Operon of Escherichia coli
Fecha
2009Registro en:
CURRENT MICROBIOLOGY, v.58, n.3, p.264-267, 2009
0343-8651
10.1007/s00284-008-9319-1
Autor
AGUENA, Meire
SPIRA, Beny
Institución
Resumen
The pst operon of Escherichia coli is composed of five genes that encode a high-affinity phosphate transport system. pst belongs to the PHO regulon, which is a group of genes and operons that are induced in response to phosphate limitation. The pst operon also has a regulatory role in the repression of PHO genes` transcription under phosphate excess conditions. Transcription of pst is initiated at the promoter located upstream to the first gene, pstS. Immediately after its synthesis, the primary transcript of pst is cleaved into shorter mRNA molecules in a ribonuclease E-dependent manner. Other ribonucleases, such as RNase III and MazF, do not play a role in pst mRNA processing. RNase E is thus at least partially responsible for processing the pst primary transcript.