Evolutionary history of Dengue virus type 4: Insights into genotype phylodynamics

dc.creatorVILLABONA-ARENAS, Christian Julian
dc.creatorZANOTTO, Paolo Marinho de Andrade
dc.date.accessioned2012-10-20T03:24:20Z
dc.date.accessioned2018-07-04T15:36:08Z
dc.date.available2012-10-20T03:24:20Z
dc.date.available2018-07-04T15:36:08Z
dc.date.created2012-10-20T03:24:20Z
dc.date.issued2011
dc.identifierINFECTION GENETICS AND EVOLUTION, v.11, n.5, p.878-885, 2011
dc.identifier1567-1348
dc.identifierhttp://producao.usp.br/handle/BDPI/28365
dc.identifier10.1016/j.meegid.2011.02.007
dc.identifierhttp://dx.doi.org/10.1016/j.meegid.2011.02.007
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1625008
dc.description.abstractDengue virus type 4 (DENV-4) circulates in tropical and subtropical countries from Asia and the Americas. Despite the importance of dengue virus distribution, little is known about the worldwide viral spread. Following a Bayesian phylogenetic approach we inferred the evolutionary history of 310 isolates sampled from 37 countries during the time period 1956-2008 and the spreading dynamics for genotypes I and II. The region (tropical rainforest biome) comprised by Malaysia-Thailand was the most likely ancestral area from which the serotype has originated and spread. Interestingly, cross-correlation analysis on demographic time series with the Asian sequences showed a statistically significant negative correlation that could be suggestive of competition among genotypes within the same serotype. (C) 2011 Elsevier B.V. All rights reserved.
dc.languageeng
dc.publisherELSEVIER SCIENCE BV
dc.relationInfection Genetics and Evolution
dc.rightsCopyright ELSEVIER SCIENCE BV
dc.rightsrestrictedAccess
dc.subjectDengue virus type 4
dc.subjectEvolution
dc.subjectPhylogeography
dc.subjectPhylodynamics
dc.titleEvolutionary history of Dengue virus type 4: Insights into genotype phylodynamics
dc.typeArtículos de revistas


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