Artículos de revistas
Reduced cytokine production by glycogen-elicited peritoneal cells from diabetic rats
Fecha
2008Registro en:
SHOCK, v.30, n.3, p.308-310, 2008
1073-2322
10.1097/SHK.0b013e318164e834
Autor
ALBA-LOUREIRO, Tatiana Carolina
PITHON-CURI, Tania Cristina
Curi, Rui
Institución
Resumen
IL-1 beta, TNF-alpha, cytokine-induced neutrophil chemoattractant-2 alpha/beta, and IL-10 measurements were performed in elicited peritoneal cells from control, diabetic, and insulin-treated diabetic rats. Production/liberation of these cytokines was decreased in elicited peritoneal cells from diabetic rats. These changes were abolished by insulin treatment of diabetic rats. The alterations observed might be involved in the impaired inflammatory response and high occurrence of apoptosis observed in neutrophils under diabetic states.