Artículos de revistas
Effect of laser phototherapy on recurring herpes labialis prevention: an in vivo study
Fecha
2010Registro en:
LASERS IN MEDICAL SCIENCE, v.25, n.3, p.397-402, 2010
0268-8921
10.1007/s10103-009-0717-9
Autor
CARVALHO, Renata Rodrigues de
EDUARDO, Fernanda de Paula
RAMALHO, Karen Mueller
ANTUNES, Jose Leopoldo Ferreira
BEZINELLI, Leticia Mello
MAGALHAES, Marina Helena Cury Gallottini de
PEGORETTI, Tatiana
FREITAS, Patricia Moreira de
EDUARDO, Carlos de Paula
Institución
Resumen
Alternative treatment for recurrent labial infection by herpes simplex virus (HSV) have been considered. The aim of this study was to evaluate the effectiveness of laser phototherapy in prevention and reduction of severity of labial manifestations of herpes labialis virus. Seventy-one patients, divided into experimental (n = 41) and control (n = 30) groups were followed up for 16 months. Patients in the control group were treated topically with aciclovir and patients in the experimental group were subjected to laser phototherapy (one session per week, 10 weeks): 780 nm, 60 mW, 3.0 J/cm(2) or 4.5 J/cm(2) on healthy (no HSV-1 infection) and affected (with HSV-1 infection) tissues. Patients in the experimental group presented a significant decrease in dimension of herpes labialis lesions (P = 0.013) and inflammatory edema (P = 0.031). The reduction in pain level (P = 0.051) and monthly recurrences (P = 0.076) did not reach statistical significance. This study represents an in vivo indication that this treatment should be further considered as an effective alternative to therapeutic regimens for herpes labialis lesions.