Artículos de revistas
Clonal Complex Chromosome Aberration in Non-Ossifying Fibroma
Fecha
2010Registro en:
PEDIATRIC BLOOD & CANCER, v.54, n.5, p.764-767, 2010
1545-5009
10.1002/pbc.22393
Autor
BRASSESCO, Maria Sol
VALERA, Elvis Terci
ENGEL, Edgard Eduard
NOGUEIRA-BARBOSA, Marcello Henrique
BECKER, Aline Paixao
SCRIDELI, Carlos Alberto
TONE, Luiz Gonzaga
Institución
Resumen
Cytogenetic information of non-ossifying fibromas (NOFs) is exceptionally limited. This fact relies, in part, on their benign nature but mainly because most cases evolve undetected or there is no need for surgical intervention. We report the case of a NOF arising in the left tibia of a 14-year-old male with an invariable clonal translocation. The karyotype was denoted as 42-46,XY,t(11;3;14)(q23;p21;p11). There are only two previous reported cases of clonally aberrant NOF. Records from additional cases will be essential to assess whether consistent karyotypic aberrations define this lesion. Pediatr Blood Cancer 2010;54:764 767. (C) 2010 Wiley-Liss, Inc.