Artículos de revistas
Pitfalls in the Differential Diagnosis of Renal Tumor in an Adolescent
Fecha
2010Registro en:
PEDIATRIC BLOOD & CANCER, v.54, n.2, p.319-321, 2010
1545-5009
10.1002/pbc.22289
Autor
VALERA, Elvis Terci
BRASSESCO, Maria Sol
CORTEZ, Maria Anglica Abdalla de Freitas
QUEIROZ, Rosane Gomes
CASTRO-GAMERO, Angel Mauricio
BARROS, Marcus Vinicius de Castro
VICENTE, Yvone Avalloni
TUCCI JUNIOR, Silvio
SCRIDELI, Carlos Alberto
TONE, Luiz Gonzaga
Institución
Resumen
The differential diagnosis of renal tumors, particularly in adolescents, may be challenging. We describe an 11-year-old female with a primary intra-renal mass. Initial differential diagnoses included primitive neuroectodermal tumor (PNET), desmoplastic small round cell tumor (DSRCT), and Wilms Turner (WT). Extensive pathologic and molecular analysis on initial and relapsed tumor samples confirmed WT. The EWS-WTI and EWS-FL11 rearrange-merits, distinctive of DSRCT and PNET were negative. The differential diagnosis on monophasic blastemal WT may be complex. Primary renal DSRCT and MET have been rarely described. Nevertheless, molecular confirmation for these rare conditions may be necessary in selected cases. Pediatr Blood Cancer 2010;54:3 19-321. (C) 2009 Wiley-Liss, Inc.