Artículos de revistas
Insertion/deletion polymorphism of the bradykinin type 2 receptor gene influence diastolic blood pressure
Fecha
2009Registro en:
JOURNAL OF HUMAN HYPERTENSION, v.23, n.8, p.553-555, 2009
0950-9240
10.1038/jhh.2009.23
Autor
FREITAS, S. R.
PEREIRA, A. C.
FLORIANO, M. S.
MILL, J. G.
KRIEGER, J. E.
Institución
Resumen
The contribution of kinins to the beneficial effects in cardiovascular risk reductions remains unclear. In this context, the present study examined whether the +9bp/-9 bp polymorphism in bradykinin type 2 receptor gene, predicts hypertension risk in a large urban Brazilian population. Our finding indicated that the -9 bp allele may contribute to hypertension because of increased diastolic pressure.