Artículos de revistas
Systemic lupus erythematosus and ""lupus dyslipoproteinemia""
Date
2008Registration in:
AUTOIMMUNITY REVIEWS, v.7, n.3, p.246-250, 2008
1568-9972
10.1016/j.autrev.2007.11.016
Author
CARVALHO, Jozelio Freire de
BONFA, Eloisa
BORBA, Eduardo Ferreira
Institutions
Abstract
A growing body of evidences reinforces the close link between systemic lupus erythematosus (SLE) and atherosclerosis which is due to traditional and nontraditional risk factors for cardiovascular diseases. It is now recognized that SLE has a particular pattern of dyslipoproteinemia characterized by low HDL levels and increased triglycerides, which is aggravated by flares. Multiple mechanisms can induce an altered lipoprotein metabolism in SLE such as cytokines produced during systemic inflammation, autoantibodies and therapy. (C) 2007 Elsevier B.V. All rights reserved.