Artículos de revistas
Adult-onset Still`s Disease with Pulmonary and Cardiac Involvement and Response to Intravenous Immunoglobulin
Fecha
2009Registro en:
ACTA REUMATOLOGICA PORTUGUESA, v.34, n.4, p.628-632, 2009
0303-464X
Autor
ROSA NETO, Nilton Salles
WALDRICH, Leandro
CARVALHO, Jozelio Freire de
PEREIRA, Rosa Maria Rodrigues
Institución
Resumen
Cardiopulmonary manifestations of adult-onset Still`s disease (AOSD) include pericarditis, pleural effusion, transient pulmonary infiltrates, pulmonary interstitial disease and myocarditis. Serositis are common but pneumonitis and myocarditis are not and bring elevated risk of mortality. They may manifest on disease onset or flares. Previously reported cases were treated with high-dose glucocorticoids and immunosupressants and, when refractory, intravenous immunoglobulin (IVIG). We report an AOSD patient whose flare presented with severe pleupneumonitis and myopericarditis and, following nonresponse to a methylprednisolone pulse, high dose of prednisone and cyclosporine A, recovered after a 2-day 1g/kg/day IVIG infusion.