Artículos de revistas
MR Spectroscopy Detects Lipid Peaks in Cerebrotendinous Xanthomatosis
AMERICAN JOURNAL OF NEURORADIOLOGY, v.31, n.7, p.1347-1349, 2010
EMBIRUCU, E. K.
OTADUY, M. C. G.
TANEJA, A. K.
LEITE, C. C.
LUCATO, L. T.
CTX is a rare lipid-storage disease. Novel MRS findings from 3 patients, using a short TE, were the presence of lipid peaks at 0.9 and 1.3 ppm in the depth of the cerebellar hemisphere; this might represent an additional marker of disease that is CNS-specific and noninvasive. A decrease in NAA concentration was also detected and attributed to neuroaxonal damage. One patient presented an increase in mlns concentration, pointing to gliosis and astrocytic proliferation.