Artículos de revistas
A Preliminary Controlled Trial of Cognitive Behavioral Therapy in Clozapine-Resistant Schizophrenia
Date
2009Registration in:
JOURNAL OF NERVOUS AND MENTAL DISEASE, v.197, n.11, p.865-868, 2009
0022-3018
10.1097/NMD.0b013e3181be7422
Author
BARRETTO, Eliza Martha de Paiva
KAYO, Monica
AVRICHIR, Belquiz S.
SA, Antonio Reis
CAMARGO, Maria das Gracas Miquelutti
NAPOLITANO, Isabel Cristina
NERY, Fabiano Goncalves
PINTO JR., Jony Arrais
BANNWART, Silvia
SCEMES, Silvia
SARNO, Elaine Di
ELKIS, Helio
Institutions
Abstract
The use of cognitive-behavior therapy (CBT) in addition to antipsychotic regimen to treat persistent psychotic symptoms of schizophrenia is growing. The aim of this study was to compare the efficacy of CBT to a befriending (BF) control group in patients with schizophrenia who are refractory to clozapine. Twenty-one patients completed the 21-week trial. In comparison with the control group, the CBT group showed a significant improvement in the General Psychopathology and total score of the Positive and Negative Syndrome Scale, as well as an improvement Of Quality of Life scale. The improvement in psychopathology persisted at 6-month follow-up assessment.