Artículos de revistas
Synthesis of (Z)-tributylstannyl enynes: systematic studies of Sonogashira cross-coupling reactions between (E)-1-iodovinyl-1-tributylstannanes and terminal acetylenes using amines or tetrabutylammonium hydroxide (TBAOH) as activator
Fecha
2011Registro en:
TETRAHEDRON LETTERS, v.52, n.32, p.4177-4181, 2011
0040-4039
10.1016/j.tetlet.2011.06.004
Autor
NAZARIO, Carlos E. D.
SANTANA, Amanda S.
KAWASOKO, Cristiane Y.
CAROLLO, Carlos A.
HURTADO, Gabriela R.
VIANA, Luiz H.
BARBOSA, Sandro L.
GUERRERO JR., Palimecio G.
MARQUES, Francisco A.
DABDOUB, Vania B.
DABDOUB, Miguel J.
BARONI, Adriano C. M.
Institución
Resumen
Sonogashira cross-coupling reactions involving (E)-iodo vinyl stannanes and terminal acetylenes were carried out in the presence of Pd(PPh(3))(4), Cul and several amines, affording (Z)-tributylstannyl enynes in moderate to good yields (62-91%). Utilizing the catalytic system containing Pd(PPh(3))(4) (5%), Cul (10%), and TBAOH (40% in aqueous media) as activator, better yields (72-91%) and lower reaction times were achieved. (C) 2011 Elsevier Ltd. All rights reserved.