Artículos de revistas
EVALUATION OF DICLORAN`S CONTRIBUTION TO THE MUTAGENIC ACTIVITY OF CRISTAIS RIVER, BRAZIL, WATER SAMPLES
Fecha
2009Registro en:
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, v.28, n.9, p.1881-1884, 2009
0730-7268
Autor
OLIVEIRA, Danielle Palma de
SAKAGAMI, Maureen
WARREN, Sarah
KUMMROW, Fabio
UMBUZEIRO, Gisela de Aragao
Institución
Resumen
2,6-Dichloro-4-nitroaniline (dicloran) is a mutagenic aromatic amine used as an agricultural fungicide and in the synthesis of disperse dyes. It is a known mutagen (Salmonella/microsome assay) in strains TA98 and TA100. Dicloran was initially detected, but not quantified, in the Cristais River, Brazil. The objective of the present study was to estimate the contribution of dicloran to mutagenic activity in samples from this river. Dicloran was found in the raw water at 0.14 mu g/L but not in the treated water. Comparison of mutagenic potencies in Salmonella strain YG1041 for dicloran and the river water sample indicated that dicloran contributed less than 0.1% of total mutagenic activity.