Artículos de revistas
Use of hyaluronidase to prevent perineal trauma during spontaneous delivery: A pilot study
Fecha
2008Registro en:
JOURNAL OF MIDWIFERY & WOMENS HEALTH, v.53, n.4, p.353-361, 2008
1526-9523
10.1016/j.jmwh.2008.02.015
Autor
SCARABOTTO, Leila Barreto
RIESCO, Maria Luiza Gonzalez
Institución
Resumen
Our objective was to compare the frequency, degree, and location of perineal trauma during spontaneous delivery with or without perineal injections of hyaluronidase (HAase). This was a randomized, controlled pilot study, conducted in a midwifie-led hospital birth center in Sao Paulo, Brazil. Primiparous women (N = 139) were randomly assigned to an intervention group (HAase injection, n = 71) or to a control group (no injection, n = 68). Significant differences were noted between the two groups in frequency of perineal trauma (intervention, 39.4%; control, 76.5%), degree of spontaneous laceration (intervention, 0.0%; control, 82.4%), and laceration located in the posterior region of the perineum (intervention, 54.2%; control, 84.3%). When episiotomy and second-degree lacerations were considered together and women with intact perineum were excluded from the analysis, the difference between the groups was no longer significant. With the use of the HAase enzyme, the relative risk was 0.5 for perineal trauma and 0.0 for second-degree lacerations. The present findings suggest that perineal injection of HAase prevented perineal trauma. These findings provide strong rationale for a larger follow-up study.