Artículos de revistas
Cadmium telluride nanocrystals as luminescent sensitizers in flow analysis
Fecha
2011Registro en:
TALANTA, v.84, n.5, Special Issue, p.1314-1317, 2011
0039-9140
10.1016/j.talanta.2011.02.041
Autor
FORTES, Paula R.
FRIGERIO, Christian
SILVESTRE, Cristina I. C.
SANTOS, Joao L. M.
LIMA, Jose L. F. C.
ZAGATTO, Elias A. G.
Institución
Resumen
A fully automated multipumping flow system (MPFS) using water-soluble CdTe quantum dots (QD) as sensitizers is proposed for the chemiluminometric determination of the anti-diabetic drugs gliclazide and glipizide in pharmaceutical formulations. The nanocrystals acted as enhancers of the weak CL emission produced upon oxidation of sulphite by Ce(IV) in acidic medium, thus improving sensitivity and expanding the dynamical analytical concentration range. By interacting with the QD, the two analytes prevented their sensitizing effect yielding a chemiluminescence quenching of the Ce(IV)-SO(3)(2-)CdTe QD system. The pulsed flow inherent to MPFS assured a fast and efficient mixing of all solutions inside the flow cell, circumventing the need for a reaction coil and facilitating the monitoring of the short-lived generated chemiluminescent species. QD crystal size, concentration and spectral region for measurement were investigated. (C) 2011 Elsevier B.V. All rights reserved.