Artículos de revistas
Follow-up after acute respiratory distress syndrome caused by influenza a (H1N1) virus infection
Fecha
2011Registro en:
Clinics, v.66, n.6, p.933-937, 2011
1807-5932
10.1590/S1807-59322011000600002
Autor
TOUFEN JR., Carlos
COSTA, Eduardo Leite V.
HIROTA, Adriana Sayuri
LI, Ho Yeh
AMATO, Marcelo Brito Passos
CARVALHO, Carlos Roberto Ribeiro
Institución
Resumen
BACKGROUND: There are no reports on the long-term follow-up of patients with swine-origin influenza A virus infection that progressed to acute respiratory distress syndrome. METHODS: Four patients were prospectively followed up with pulmonary function tests and high-resolution computed tomography for six months after admission to an intensive care unit. RESULTS: Pulmonary function test results assessed two months after admission to the intensive care unit showed reduced forced vital capacity in all patients and low diffusion capacity for carbon monoxide in two patients. At six months, pulmonary function test results were available for three patients. Two patients continued to have a restrictive pattern, and none of the patients presented with abnormal diffusion capacity for carbon monoxide. All of them had a diffuse ground-glass pattern on high-resolution computed tomography that improved after six months. CONCLUSIONS: Despite the marked severity of lung disease at admission, patients with acute respiratory distress syndrome caused by swine-origin influenza A virus infection presented a late but substantial recovery over six months of follow-up.