Síntese de glicoaminoácidos de interesse biológico

dc.creatorCAMPO, Vanessa Leiria
dc.creatorCARVALHO, Ivone
dc.date.accessioned2012-03-26T14:01:48Z
dc.date.accessioned2018-07-04T13:59:21Z
dc.date.available2012-03-26T14:01:48Z
dc.date.available2018-07-04T13:59:21Z
dc.date.created2012-03-26T14:01:48Z
dc.date.issued2008
dc.identifierQuímica Nova, v.31, n.5, p.1027-1033, 2008
dc.identifier0100-4042
dc.identifierhttp://producao.usp.br/handle/BDPI/5809
dc.identifier10.1590/S0100-40422008000500015
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000500015
dc.identifierhttp://www.scielo.br/pdf/qn/v31n5/a15v31n5.pdf
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1604384
dc.description.abstractThis work describes the synthesis of the glycosylated amino acids αGlcNAc-Thr, βGlcNAc-Thr and αLacNAc-Thr by the glycosylation reaction of the amino acid threonine with the corresponding glycosyl donors αGlcNAcCl and αLacN3Cl. The glycosylated amino acids containing the sugar units α-D-GlcNAc and α-D-LacNAc O-linked to threonine amino acids are related to O-glycans found in mucins of the parasite Trypanosoma cruzi, while the corresponding β-D-GlcNAc isomer is involved in cellular signaling events.
dc.languagepor
dc.publisherSociedade Brasileira de Química
dc.relationQuímica Nova
dc.rightsCopyright Sociedade Brasileira de Química
dc.rightsopenAccess
dc.subjectGlycosylated amino acids
dc.subjectGlycosyl donors
dc.subjectGlycosylation reaction
dc.titleSíntese de glicoaminoácidos de interesse biológico
dc.typeArtículos de revistas


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