Artículos de revistas
Multidrug-resistant Pathogenic Escherichia Coli Isolated From Wild Birds In A Veterinary Hospital
Registro en:
Avian Pathology. Taylor & Francis Ltd, v. 46, p. 76 - 83, 2017.
0307-9457
1465-3338
WOS:000392623900009
10.1080/03079457.2016.1209298
Autor
Borges
C. A.; Beraldo
L. G.; Maluta
R. P.; Cardozo
M. V.; Barboza
K. B.; Guastalli
E. A. L.; Kariyawasam
S.; DebRoy
C.; Avila
F. A.
Institución
Resumen
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Wild birds are carriers of Escherichia coli. However, little is known about their role as reservoirs for extra-intestinal pathogenic E. coli (ExPEC). In this work we investigated E. coli strains carrying virulence genes related to human and animal ExPEC isolated from free-living wild birds treated in a veterinary hospital. Multidrug resistance was found in 47.4% of the strains, but none of them were extended-spectrum beta-lactamase producers. Not only the virulence genes, but also the serogroups (e.g. O1 and O2) detected in the isolates of E. coli have already been implicated in human and bird diseases. The sequence types detected were also found in wild, companion and food animals, environmental and human clinical isolates in different countries. Furthermore, from the 19 isolates, 17 (89.5%) showed a degree of pathogenicity on an in vivo infection model. The isolates showed high heterogeneity by pulsed-field gel electrophoresis indicating that E. coli from these birds are clonally diverse. Overall, the results showed that wild birds can be reservoirs and/or vectors of highly pathogenic and multidrug-resistant E. coli that have the potential to cause disease in humans and poultry. 46 1 76 83 Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2008/00417-0, 2010/12002-0, 2011/06467-2] Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)