Terms Of Endearment: Bacteria Meet Graphene Nanosurfaces

dc.creatorTegou
dc.creatorEvangelia; Magana
dc.creatorMaria; Katsogridaki
dc.creatorAlexandra Eleni; Ioannidis
dc.creatorAnastasios; Raptis
dc.creatorVasilios; Jordan
dc.creatorSheldon; Chatzipanagiotou
dc.creatorStylianos; Chatzandroulis
dc.creatorStavros; Ornelas
dc.creatorCatia; Tegos
dc.creatorGeorge P.
dc.date2016
dc.datemaio
dc.date2017-11-13T13:54:24Z
dc.date2017-11-13T13:54:24Z
dc.date.accessioned2018-03-29T06:07:47Z
dc.date.available2018-03-29T06:07:47Z
dc.identifierBiomaterials . Elsevier Sci Ltd , v. 89, p. 38 - 55, 2016.
dc.identifier0142-9612
dc.identifier1878-5905
dc.identifierWOS:000374072500004
dc.identifier10.1016/j.biomaterials.2016.02.030
dc.identifierhttp://www.sciencedirect.com/science/article/pii/S0142961216001447?via%3Dihub
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/329389
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1366414
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionMicrobial multidrug resistance poses serious risks in returning the human species into the pre-antibiotic era if it remains unsolved. While conventional research approaches to combat infectious diseases have been inadequate, nanomaterials are a promising alternative for the development of sound antimicrobial countermeasures. Graphene, a two-dimensional ultra-thin nanomaterial, possesses excellent electronic and biocompatibility properties, which position it in the biotechnology forefront for diverse applications in biosensing, therapeutics, diagnostics, drug delivery and device development. Yet, several questions remain unanswered. For instance, the way these nanosurfaces interact with the microbial entities is poorly understood. The mechanistic elucidation of this interface seems critical to determine the feasibility of applications under development. Are graphene derivatives appropriate materials to design potent antimicrobial agents, vehicles or effective diagnostic microsensors? Has the partition of major microbial resistance phenotypic determinants been sufficiently investigated? Can toxicity become a limiting factor? Are we getting closer to clinical implementation? To facilitate research conducive to answer such questions, this review describes the features of the graphene bacterial interaction. An overview on paradigms of graphene microbial interactions is expected to shed light on the range of materials available, and identify possible applications, serving the ultimate goal to develop deeper understanding and collective conscience for the true capabilities of this nanomaterial platform. (C) 2016 Elsevier Ltd. All rights reserved.
dc.description89
dc.description38
dc.description55
dc.descriptionGreek State Scholarships Foundation (IKY grant) under the IKY fellowships of excellence for postgraduate studies in Greece-Siemens program [2013/22056]
dc.descriptionSao Paulo Research Foundation (FAPESP) [2013/11519-7]
dc.descriptionGreek Public Benefit Foundation "Lilian Voudouri" [2014/272]
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageEnglish
dc.publisherElsevier Sci LTD
dc.publisherOxford
dc.relationBiomaterials
dc.rightsfechado
dc.sourceWOS
dc.subjectGraphene
dc.subjectCarbon Allotropes
dc.subjectNanosurfaces
dc.subjectAntimicrobial Resistance
dc.subjectBiocompatible Therapeutics
dc.subjectBiosensing
dc.titleTerms Of Endearment: Bacteria Meet Graphene Nanosurfaces
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución