Wernicke's Encephalopathy Mimicking Neuropsychiatric Symptoms In Patients With Systemic Lupus Erythematosus: A Report Of Three Cases And Literature Review

dc.creatorAppenzeller
dc.creatorS.; Reis
dc.creatorF.; Costallat
dc.creatorL. T. Lavras; Perez
dc.creatorJ. Adams; Saldanha
dc.creatorC. F.; Monticielo
dc.creatorO. A.
dc.date2017
dc.datefev
dc.date2017-11-13T13:12:40Z
dc.date2017-11-13T13:12:40Z
dc.date.accessioned2018-03-29T05:50:50Z
dc.date.available2018-03-29T05:50:50Z
dc.identifierLupus. Sage Publications Ltd, v. 26, p. 195 - 199, 2017.
dc.identifier0961-2033
dc.identifier1477-0962
dc.identifierWOS:000392615400011
dc.identifier10.1177/0961203316658556
dc.identifierhttp://journals.sagepub.com/doi/full/10.1177/0961203316658556
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/326922
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1363947
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionSystemic lupus erythematosus (SLE) is a chronic inflammatory disease that involves many organs and systems. Nervous system involvement in SLE encompasses neurological and psychiatric disorders, and remains a diagnostic and therapeutic challenge. Wernicke's encephalopathy (WE) is a neurological disorder that occurs as a consequence of thiamine deficiency, and its clinical presentation resembles the neuropsychiatric events attributed to SLE (NPSLE). Differentiation between these two entities is crucial because their treatment differs greatly and can change prognosis. We describe three cases of patients with SLE who presented with initial clinical findings suggestive of NPSLE that, at the end of a thorough clinical investigation, were actually found to represent WE. In all of these cases, treatment with thiamine resulted in significant improvement. WE should be considered as a differential diagnosis in SLE patients with neuropsychiatric signs and symptoms, especially when risk factors for thiamine deficiency are present.
dc.description26
dc.description2
dc.description195
dc.description199
dc.descriptionResearch Incentive Fund (Fundo de Incentivo a Pesquisa e Eventos, FIPE) of Hospital de Clinicas de Porto Alegre
dc.descriptionCoordination for the Improvement of Higher Education Personnel (Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior, CAPES)
dc.descriptionNational Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Cientifico e Tecnologico, CNPq)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageEnglish
dc.publisherSage Publications LTD
dc.publisherLondon
dc.relationLupus
dc.rightsfechado
dc.sourceWOS
dc.subjectWernicke's Encephalopathy
dc.subjectSystemic Lupus Erythematosus
dc.subjectNeuropsychiatric Lupus
dc.titleWernicke's Encephalopathy Mimicking Neuropsychiatric Symptoms In Patients With Systemic Lupus Erythematosus: A Report Of Three Cases And Literature Review
dc.typeArtículos de revistas


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