Artículos de revistas
Diastolic Dysfunction And Hypertension
Registro en:
Medical Clinics Of North America. W B Saunders Co-elsevier Inc, v. 101, p. 7 - +, 2017.
0025-7125
1557-9859
WOS:000390970600004
10.1016/j.mcna.2016.08.013
Autor
Nadruz
Wilson; Shah
Amil M.; Solomon
Scott D.
Institución
Resumen
Left ventricular (LV) diastolic dysfunction (LVDD) is characterized by alterations in LV diastolic filling, and is a strong predictor of cardiovascular events and heart failure. Hypertension is the most important risk factor for LVDD in the community and promotes LVDD through several mechanisms, including hemodynamic overload and myocardial ischemia. Associated factors such as age, ethnicity, dietary sodium, obesity, diabetes mellitus, and chronic kidney disease also contribute to LVDD in hypertensive individuals. Blood pressure lowering using antihypertensive medications can improve LVDD; however, it remains unclear whether this improvement in LV diastolic function can improve cardiovascular outcomes. 101 1 7 +