This overview highlights the importance of characterization of biogenic nanoparticles of silver and silver chloride in order to understand the action on ticks or pathogens transmitted by them. These nanoparticles appear as important active principles in this area. They can act against ticks or against major pathogens transmitted by the bite of ticks such as bacteria, viruses or protozoa with equal or better efficacy of antibiotics, antiviral or antiparasitic agents. Anti-tick activities on Rhipicephalus (Boophilus) microplus, Hyalomma anatolicum, Hyalomma isaaci and Haemaphysalis bispinosa are discussed. Perspectives of these nanoparticles acting on bacteria, viruses and protozoa infections are also discussed.286927932