Artículos de revistas
Cardioprotective Properties Of Aerobic And Resistance Training Against Myocardial Infarction
Registro en:
1439-3964
International Journal Of Sports Medicine. GEORG THIEME VERLAG KG, n. 37, n. 6, p. 421 - 430.
1439-3964
WOS:000377991200001
10.1055/s-0035-1565136
Autor
Barboza
CA; Souza
GIH; Oliveira
JCMF; Silva
LM; Mostarda
CT; Dourado
PMM; Oyama
LM; Lira
FS; Irigoyen
MC; Rodrigues
B
Institución
Resumen
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) We evaluated the effects of aerobic and resistance exercise training on ventricular morphometry and function, physical capacity, autonomic function, as well as on ventricular inflammatory status in trained rats prior to myocardial infarction. Male Wistar rats were divided into the following groups: sedentary+Sham, sedentary+myocardial infarction, aerobic trained+myocardial infarction, and resistance trained+myocardial infarction. Sham and myocardial infarction were performed after training periods. In the days following the surgeries, evaluations were performed. Aerobic training prevents aerobic (to a greater extent) and resistance capacity impairments, ventricular dysfunction, baroreflex sensitivity and autonomic disorders (vagal tonus decrease and sympathetic tonus increase) triggered by myocardial infarction. Resistance training was able to prevent negative changes to aerobic and resistance capacity (to a greater extent) but not to ventricular dysfunction, and it prevented cardiovascular sympathetic increments. Additionally, both types of training reduced left ventricle inflammatory cytokine concentration. Our results suggest that aerobic and, for the first time, dynamic resistance training were able to reduce sympathetic tonus to the heart and vessels, as well as preventing the increase in pro-inflammatory cytokine concentrations in the left ventricle of trained groups. These data emphasizes the positive effects of aerobic and dynamic resistance training on the prevention of the negative changes triggered by myocardial infarction. 37
421 430 Fundacao de Amparo a Pesquisa do Estado de Sao Paulo, Brazil [FAPESP - 2013/14788-9, FAPESP - 2014/06669-2] Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)