Screening Of Miners And Millers At Decreasing Levels Of Asbestos Exposure: Comparison Of Chest Radiography And Thin-section Computed Tomography

dc.creatorTerra-Filho
dc.creatorMario; Bagatin
dc.creatorEricson; Nery
dc.creatorLuiz Eduardo; Napolis
dc.creatorLara Maris; Neder
dc.creatorJose Alberto; Portes Meirelles
dc.creatorGustavo de Souza; Isabela Silva
dc.creatorC.; Muller
dc.creatorNestor L.
dc.date2015-Mar
dc.date2016-06-07T13:18:40Z
dc.date2016-06-07T13:18:40Z
dc.date.accessioned2018-03-29T01:38:59Z
dc.date.available2018-03-29T01:38:59Z
dc.identifier
dc.identifierScreening Of Miners And Millers At Decreasing Levels Of Asbestos Exposure: Comparison Of Chest Radiography And Thin-section Computed Tomography. Public Library Science, v. 10, p. Mar-2015.
dc.identifier1932-6203
dc.identifierWOS:000351425400036
dc.identifier10.1371/journal.pone.0118585
dc.identifierhttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118585
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/242551
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1306249
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionBackground Chest radiography (CXR) is inferior to Thin-section computed tomography in the detection of asbestos related interstitial and pleural abnormalities. It remains unclear, however, whether these limitations are large enough to impair CXR's ability in detecting the expected reduction in the frequency of these asbestos-related abnormalities (ARA) as exposure decreases. Methods Clinical evaluation, CXR, Thin-section CT and spirometry were obtained in 1418 miners and millers who were exposed to progressively lower airborne concentrations of asbestos. They were separated into four groups according to the type, period and measurements of exposure and/or procedures for controlling exposure: Group I (1940-1966/tremolite and chrysotile, without measurements of exposure and procedures for controlling exposure); Group II (1967-1976/chrysotile only, without measurements of exposure and procedures for controlling exposure); Group III (1977-1980/chrysotile only, initiated measurements of exposure and procedures for controlling exposure) and Group IV (after 1981/chrysotile only, implemented measurements of exposure and a comprehensive procedures for controlling exposure). Results In all groups, CXR suggested more frequently interstitial abnormalities and less frequently pleural plaques than observed on Thin-section CT (p < 0.050). The odds for asbestosis in groups of decreasing exposure diminished to greater extent at Thin-section CT than on CXR. Lung function was reduced in subjects who had pleural plaques evident only on Thin-section CT (p < 0.050). In a longitudinal evaluation of 301 subjects without interstitial and pleural abnormalities on CXR and Thin-section CT in a previous evaluation, only Thin-section CT indicated that these ARA reduced as exposure decreased. Conclusions CXR compared to Thin-section CT was associated with false-positives for interstitial abnormalities and false-negatives for pleural plaques, regardless of the intensity of asbestos exposure. Also, CXR led to a substantial misinformation of the effects of the progressively lower asbestos concentrations in the occurrence of asbestos-related diseases in miners and millers.
dc.description10
dc.description3
dc.description
dc.description
dc.description
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFUNAPE - Goias State Government [54.023]
dc.descriptionSAMA [2P-04559-98]
dc.descriptionBrazilian Crysotile Institute (IBC)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFAPESP [1996/10415-6]
dc.description
dc.description
dc.description
dc.languageen
dc.publisherPUBLIC LIBRARY SCIENCE
dc.publisher
dc.publisherSAN FRANCISCO
dc.relationPLOS ONE
dc.rightsaberto
dc.sourceWOS
dc.subjectHigh-resolution Ct
dc.subjectPleural Plaques
dc.subjectLung-function
dc.subjectWorkers
dc.subjectDisease
dc.subjectFibrosis
dc.subjectSmoking
dc.subjectAbnormalities
dc.subjectManagement
dc.titleScreening Of Miners And Millers At Decreasing Levels Of Asbestos Exposure: Comparison Of Chest Radiography And Thin-section Computed Tomography
dc.typeArtículos de revistas


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