Characterization Of Binary And Ternary Mixtures Of Green, White And Black Tea Extracts By Electrospray Ionization Mass Spectrometry And Modeling Of Their In Vitro Antibacterial Activity

dc.creatorGranato
dc.creatorDaniel; do Prado-Silva
dc.creatorLeonardo; Alvarenga
dc.creatorVeronica O.; Zielinski
dc.creatorAcacio A. F.; Bataglion
dc.creatorGiovana A.; de Morais
dc.creatorDamila R.; Eberlin
dc.creatorMarcos N.; Sant'Ana
dc.creatorAnderson de S.
dc.date2016-JAN
dc.date2016-06-07T13:14:27Z
dc.date2016-06-07T13:14:27Z
dc.date.accessioned2018-03-29T01:35:13Z
dc.date.available2018-03-29T01:35:13Z
dc.identifier
dc.identifierCharacterization Of Binary And Ternary Mixtures Of Green, White And Black Tea Extracts By Electrospray Ionization Mass Spectrometry And Modeling Of Their In Vitro Antibacterial Activity. Elsevier Science Bv, v. 65, p. 414-420 JAN-2016.
dc.identifier0023-6438
dc.identifierWOS:000364796700054
dc.identifier10.1016/j.lwt.2015.08.037
dc.identifierhttp://www.sciencedirect.com/science/article/pii/S0023643815301316
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/241640
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1305338
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionIn this study we modeled the in vitro antibacterial activity of the extracts of green, white and black tea mixtures using the response surface methodology. Camellia sinensis var sinensis tea mixtures were prepared according to a 3-component simplex-centroid design containing ten formulations. The antibacterial activity was used to assess the inhibition ability of the tea mixtures against a range of seven Gram positive, Gram negative, vegetative cells and sporeforming bacteria. A formulation of tea mixtures was then optimized by the desirability function aiming to maximize the inhibition of different strains and/or serotypes of Salmonella. The best tea formulation was chemically characterized by electrospray ionization mass spectrometry (ESI-MS). The linear effects of white and black teas were statistically significant (p < 0.05) as well as the interaction between green and white and green and black on the inhibition of S. Thyphimurium. Although the optimized tea mixture was effective against all Salmonella strains, the inhibition was substantially greater for specific serotypes, with differences observed even among strains of the same serotype (p < 0.05). A total of 11 phenolic constituents such as gallic acid, quinic acid, (+)-catechin/(-)-epicatechin, (-)-gallocatechin/(-)-epigalocatechin, coumaroylquinic acid, galloylquinic acid, and caffeoylquinic acid were tentatively identified using ESI-MS. (C) 2015 Elsevier Ltd. All rights reserved.
dc.description65
dc.description
dc.description
dc.description414
dc.description420
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionCNPq [302763/2014-7]
dc.description
dc.description
dc.description
dc.languageen
dc.publisherELSEVIER SCIENCE BV
dc.publisher
dc.publisherAMSTERDAM
dc.relationLWT-FOOD SCIENCE AND TECHNOLOGY
dc.rightsembargo
dc.sourceWOS
dc.subjectResponse-surface Methodology
dc.subjectMate Ilex-paraguariensis
dc.subjectAntimicrobial Activities
dc.subjectCamellia-sinensis
dc.subjectPhenolic-compounds
dc.subjectListeria-monocytogenes
dc.subjectSalmonella-enterica
dc.subjectStrain Variability
dc.subjectFood-science
dc.subjectAntioxidant
dc.titleCharacterization Of Binary And Ternary Mixtures Of Green, White And Black Tea Extracts By Electrospray Ionization Mass Spectrometry And Modeling Of Their In Vitro Antibacterial Activity
dc.typeArtículos de revistas


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