Fatty Acids As Modulators Of Neutrophil Recruitment, Function And Survival.

dc.creatorRodrigues, Hosana G
dc.creatorTakeo Sato, Fabio
dc.creatorCuri, Rui
dc.creatorVinolo, Marco A R
dc.date2015-May
dc.date2016-05-23T19:42:43Z
dc.date2016-05-23T19:42:43Z
dc.date.accessioned2018-03-29T01:29:58Z
dc.date.available2018-03-29T01:29:58Z
dc.identifierEuropean Journal Of Pharmacology. , 2015-May.
dc.identifier1879-0712
dc.identifier10.1016/j.ejphar.2015.03.098
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/25987417
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/235812
dc.identifier25987417
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1304055
dc.descriptionNeutrophils are well-known to act in the destruction of invading microorganisms. They have also been implicated in the activation of other immune cells including B- and T-lymphocytes and in the resolution of inflammation and tissue regeneration. Neutrophils are produced in the bone marrow and released into the circulation from where they migrate to tissues to perform their effector functions. Neutrophils are in constant contact with fatty acids that can modulate their function, activation and fate (survival or cell death) through different mechanisms. In this review, the effects of fatty acids pertaining to five classes, namely, long-chain saturated fatty acids (LCSFAs), short-chain fatty acids (SCFAs), and omega-3 (n-3), omega-6 (n-6) and omega-9 (n-9) unsaturated fatty acids, on neutrophils and the relevance of these effects for disease development are discussed.
dc.description
dc.description
dc.languageeng
dc.relationEuropean Journal Of Pharmacology
dc.relationEur. J. Pharmacol.
dc.rightsembargo
dc.sourcePubMed
dc.subjectAcetic Acid (pubchem Cid 176)
dc.subjectButyric Acid (pubchem Cid 264)
dc.subjectCell Function
dc.subjectDocosahexaenoic Acid (pubchem Cid 445580)
dc.subjectEicosapentaenoic Acid (pubchem Cid 446284)
dc.subjectInflammation
dc.subjectLinoleic Acid (pubchem Cid 864)
dc.subjectNeutrophil
dc.subjectOleic Acid (pubchem Cid 445639)
dc.subjectPalmitic Acid (pubchem Cid 985)
dc.subjectPropionic Acid (pubchem Cid 1032)
dc.subjectSaturated Fatty Acid
dc.subjectShort Chain Fatty Acids
dc.subjectStearic Acid (pubchem Cid 5281)
dc.subjectUnsaturared Fatty Acid
dc.titleFatty Acids As Modulators Of Neutrophil Recruitment, Function And Survival.
dc.typeArtículos de revistas


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