Artículos de revistas
Maximal Testosterone Suppression In Prostate Cancer--free Vs Total Testosterone.
Registro en:
Urology. v. 83, n. 6, p. 1217-22, 2014-Jun.
1527-9995
10.1016/j.urology.2014.02.001
24713136
Autor
Rove, Kyle O
Crawford, E David
Perachino, Massimo
Morote, Juan
Klotz, Laurence
Lange, Paul H
Andriole, Gerald L
Matsumoto, Alvin M
Taneja, Samir S
Eisenberger, Mario A
Reis, Leonardo O
Institución
Resumen
Testosterone remains a key target in the treatment of advanced prostate cancer. The relationship of free testosterone to prostate cancer treatment and outcomes remains largely unexplored. A consensus of prostate cancer experts was convened in 2013 to review current knowledge surrounding relationship of total and free testosterone to prostate cancer, discuss the free hormone hypothesis, and highlight future avenues for therapeutics. Free testosterone may better reflect prostate cancer tissue androgen levels than serum total testosterone concentration. Free testosterone deserves more research regarding its relation to clinical outcomes. 83 1217-22