Artículos de revistas
Neuromuscular Activity Of Bothrops Alcatraz Snake Venom In Chick Biventer Cervicis Preparations.
Registro en:
Toxicon : Official Journal Of The International Society On Toxinology. v. 59, n. 2, p. 294-9, 2012-Feb.
1879-3150
10.1016/j.toxicon.2011.11.011
22155137
Autor
de Moraes, Delkia Seabra
Aparecido de Abreu, Valdemir
Rostelato-Ferreira, Sandro
Leite, Gildo B
Alice da Cruz-Höfling, Maria
Travaglia-Cardoso, Silvia R
Hyslop, Stephen
Rodrigues-Simioni, Léa
Institución
Resumen
Venom (10-100 μg/ml) from Bothrops alcatraz, a pitviper from the Alcatrazes Archipelago off the coast of southeastern Brazil, caused progressive, irreversible neuromuscular blockade in chick isolated biventer cervicis preparations. The venom also inhibited contractures to exogenous ACh (110 μM) and KCl (20 mM), caused myofiber damage and increased creatine kinase release. Commercial bothropic antivenom raised against mainland Bothrops species neutralized the neuromuscular activity, depending on the venom concentration. 59 294-9