Age-related Changes In Dystrophin-glycoprotein Complex And In Utrophin Are Not Correlated With Intrinsic Laryngeal Muscles Protection In Mdx Mice.

dc.creatorFerretti, Renato
dc.creatorPertille, Adriana
dc.creatorSanto Neto, Humberto
dc.creatorMarques, Maria Julia
dc.date2011-Dec
dc.date2015-11-27T13:22:03Z
dc.date2015-11-27T13:22:03Z
dc.date.accessioned2018-03-29T01:14:10Z
dc.date.available2018-03-29T01:14:10Z
dc.identifierMuscle & Nerve. v. 44, n. 6, p. 978-80, 2011-Dec.
dc.identifier1097-4598
dc.identifier10.1002/mus.22235
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/22102469
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199697
dc.identifier22102469
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1299930
dc.descriptionIn this study we investigate whether dystrophic intrinsic laryngeal muscles (ILM) from aged mdx mice show alterations in dystrophin-glycoprotein complex (DGC) components.Immunofluorescence and immunoblotting analyses of beta-sarcoglycan, beta-dystroglycan, and utrophin showed that aged ILM had a similar pattern of changes in aged affected muscles (diaphragm and limb), suggesting that aging leads to changes in utrophin and DGC proteins in dystrophic ILM that cannot be correlated with their protection from dystrophic change.
dc.description44
dc.description978-80
dc.languageeng
dc.relationMuscle & Nerve
dc.relationMuscle Nerve
dc.rightsfechado
dc.rightsCopyright © 2011 Wiley Periodicals, Inc.
dc.sourcePubMed
dc.subjectAging
dc.subjectAnimals
dc.subjectDystroglycans
dc.subjectDystrophin
dc.subjectGlycoproteins
dc.subjectLaryngeal Muscles
dc.subjectMale
dc.subjectMice
dc.subjectMice, Inbred C57bl
dc.subjectMice, Inbred Mdx
dc.subjectMuscular Dystrophy, Animal
dc.subjectSarcoglycans
dc.subjectUtrophin
dc.titleAge-related Changes In Dystrophin-glycoprotein Complex And In Utrophin Are Not Correlated With Intrinsic Laryngeal Muscles Protection In Mdx Mice.
dc.typeArtículos de revistas


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