dc.creatorAppenzeller, Simone
dc.creatorFattori, Andre
dc.creatorSaad, Sarita T
dc.creatorCostallat, Lilian T L
dc.date2008-Mar
dc.date2015-11-27T13:13:18Z
dc.date2015-11-27T13:13:18Z
dc.date.accessioned2018-03-29T01:07:42Z
dc.date.available2018-03-29T01:07:42Z
dc.identifierClinical Rheumatology. v. 27, n. 3, p. 359-64, 2008-Mar.
dc.identifier0770-3198
dc.identifier10.1007/s10067-007-0779-7
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/18000698
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/198027
dc.identifier18000698
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1298260
dc.descriptionSickle cell disease (SCD) is a prevalent genetic disorder that includes sickle cell anemia (hemoglobin SS), hemoglobin SC, and hemoglobin Sb-thalassemia. Patients with SCD present with a defective activation of the alternate pathway of the complement system that increases the risk of capsulate bacteria infection and failure to eliminate antigens, predisposing these patients to autoimmune diseases. The authors describe three patients with SCD that developed systemic lupus erythematosus (SLE). In all patients, SLE diagnosis was delayed because symptoms were initially attributable to SCD. Physicians should be alerted to the possible development of SLE in patients with SCD to not delay the diagnosis and start appropriate treatment.
dc.description27
dc.description359-64
dc.languageeng
dc.relationClinical Rheumatology
dc.relationClin. Rheumatol.
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAnemia, Sickle Cell
dc.subjectFemale
dc.subjectHumans
dc.subjectLupus Erythematosus, Systemic
dc.subjectMale
dc.subjectMiddle Aged
dc.titleSystemic Lupus Erythematosus In Patients With Sickle Cell Disease.
dc.typeArtículos de revistas


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