Mri Shows Dorsal Lesions And Spinal Cord Atrophy In Chronic Sensory Neuronopathies.

dc.creatorFrança, Marcondes C
dc.creatorD'Abreu, Anelyssa
dc.creatorZanardi, Verônica A
dc.creatorFaria, Andréia V
dc.creatorLopes-Cendes, Iscia
dc.creatorNucci, Anamarli
dc.creatorCendes, Fernando
dc.date2008-Apr
dc.date2015-11-27T13:12:39Z
dc.date2015-11-27T13:12:39Z
dc.date.accessioned2018-03-29T01:06:32Z
dc.date.available2018-03-29T01:06:32Z
dc.identifierJournal Of Neuroimaging : Official Journal Of The American Society Of Neuroimaging. v. 18, n. 2, p. 168-72, 2008-Apr.
dc.identifier1051-2284
dc.identifier10.1111/j.1552-6569.2007.00193.x
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/18380696
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/197732
dc.identifier18380696
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1297965
dc.descriptionSensory neuronopathies (SN) represent a specific subgroup of peripheral nervous system diseases, characterized by degeneration of dorsal root ganglia (DRG) and its projections. We tried to estimate the frequency and extent of spinal cord MRI abnormalities in a group of patients with SN and correlate these with clinical and neurophysiological features. We performed spinal cord MRI scans in 16 chronic SN patients. Images were analyzed for the presence of posterior hyperintense lesions on T2WI and cord areas at C3 level were obtained using a previously validated method. A group of 14 healthy controls with similar age and gender distribution was used for comparison. ANOVA was employed for statistical analysis. Posterior T2WI lesions were found in 13 out of 16 patients. Cord areas were significantly smaller in SN patients than controls (84.3 x 97.2 mm(2), P < .05). Atrophy correlated with severity of sensory ataxia and neurophysiologic abnormalities but not with duration of disease. These findings support volumetric spinal cord MRI as a useful tool in the assessment of chronic SN.
dc.description18
dc.description168-72
dc.languageeng
dc.relationJournal Of Neuroimaging : Official Journal Of The American Society Of Neuroimaging
dc.relationJ Neuroimaging
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAnalysis Of Variance
dc.subjectAtrophy
dc.subjectCase-control Studies
dc.subjectChronic Disease
dc.subjectFemale
dc.subjectHereditary Sensory And Autonomic Neuropathies
dc.subjectHumans
dc.subjectImage Processing, Computer-assisted
dc.subjectLinear Models
dc.subjectMagnetic Resonance Imaging
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectSpinal Cord
dc.titleMri Shows Dorsal Lesions And Spinal Cord Atrophy In Chronic Sensory Neuronopathies.
dc.typeArtículos de revistas


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