Oncocytic Metaplasia In Inflammatory Fibrous Hyperplasia: Histopathological And Immunohistochemical Analysis.

dc.creatorRangel, Ana Lúcia Carrinho Ayrosa
dc.creatorLeón, Jorge Esquiche
dc.creatorJorge, Jacks
dc.creatorLopes, Márcio Ajudarte
dc.creatorVargas, Pablo Agustín
dc.date2008-Mar
dc.date2015-11-27T13:12:32Z
dc.date2015-11-27T13:12:32Z
dc.date.accessioned2018-03-29T01:06:21Z
dc.date.available2018-03-29T01:06:21Z
dc.identifierMedicina Oral, Patología Oral Y Cirugía Bucal. v. 13, n. 3, p. E151-5, 2008-Mar.
dc.identifier1698-6946
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/18305433
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/197689
dc.identifier18305433
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1297922
dc.descriptionOncocytic metaplasia (OM) is not a well-known feature in inflammatory fibrous hyperplasia (IFH) lesions, although it may be common, as proposed in our previous study about this lesion. In the present paper, we assessed the histopathological and immunohistochemical features of 18 cases of IFH containing OM areas. All the samples were examined on haematoxylin and eosin stained sections and cytokeratins (AE1/AE3, 34betaE12, CK5, CK7, CK8, CK13, CK14 and CK19), CD15, CD20, CD68, CD45Ro, and LCA primary antibodies were used. The vast majority of IFH occurred in women (n=14) and the most common site of presentation was the buccal vestibule. Oncocytic and salivary duct cells showed uniform immunoreactivity for AE1/AE3, CK7, CK8 and CK19. CD45Ro+ T-lymphocytes were the most common inflammatory cells surrounding the OM areas followed by CD20+ B-lymphocytes. These findings suggest that oncocytic cells present in IFH might develop from salivary duct epithelium, and T-lymphocytes might play an important role in its etiopathogenesis.
dc.description13
dc.descriptionE151-5
dc.languageeng
dc.relationMedicina Oral, Patología Oral Y Cirugía Bucal
dc.relationMed Oral Patol Oral Cir Bucal
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAged
dc.subjectAged, 80 And Over
dc.subjectFemale
dc.subjectFibrosis
dc.subjectHumans
dc.subjectHyperplasia
dc.subjectImmunohistochemistry
dc.subjectInflammation
dc.subjectMale
dc.subjectMetaplasia
dc.subjectMiddle Aged
dc.subjectMouth Mucosa
dc.titleOncocytic Metaplasia In Inflammatory Fibrous Hyperplasia: Histopathological And Immunohistochemical Analysis.
dc.typeArtículos de revistas


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