Artículos de revistas
High Expression Of Fmnl1 Protein In T Non-hodgkin's Lymphomas.
Registro en:
Leukemia Research. v. 30, n. 6, p. 735-8, 2006-Jun.
0145-2126
10.1016/j.leukres.2005.10.003
16494944
Autor
Favaro, Patricia M B
Traina, Fabiola
Vassallo, Jose
Brousset, Pierre
Delsol, George
Costa, Fernando F
Saad, Sara T O
Institución
Resumen
We recently cloned a novel Formin-family human gene, denominated human leukocyte formin and posteriorly named as FMNL1 by the HUGO Gene Nomenclature Committee. This gene is overexpressed in lymphoid malignances and is found associated with Akt. Here, we describe the expression of the FMNL1 protein in 54 frozen biopsies of non-Hodgkin's lymphoma (NHL) patients and five reactive lymph nodes. Western blot analysis revealed expression of FMNL1 in all samples studied, although the highest expression was in T-cell NHL (P<0.05). 30 735-8