The Prima Donna Of Epigenetics: The Regulation Of Gene Expression By Dna Methylation.

dc.creatorSantos, K F
dc.creatorMazzola, T N
dc.creatorCarvalho, H F
dc.date2005-Oct
dc.date2015-11-27T13:02:27Z
dc.date2015-11-27T13:02:27Z
dc.date.accessioned2018-03-29T01:01:27Z
dc.date.available2018-03-29T01:01:27Z
dc.identifierBrazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas / Sociedade Brasileira De Biofísica ... [et Al.]. v. 38, n. 10, p. 1531-41, 2005-Oct.
dc.identifier0100-879X
dc.identifier/S0100-879X2005001000010
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/16172746
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/196422
dc.identifier16172746
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1296655
dc.descriptionThis review focuses on the mechanisms of DNA methylation, DNA methylation pattern formation and their involvement in gene regulation. Association of DNA methylation with imprinting, embryonic development and human diseases is discussed. Furthermore, besides considering changes in DNA methylation as mechanisms of disease, the role of epigenetics in general and DNA methylation in particular in transgenerational carcinogenesis, in memory formation and behavior establishment are brought about as mechanisms based on the cellular memory of gene expression patterns.
dc.description38
dc.description1531-41
dc.languageeng
dc.relationBrazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas / Sociedade Brasileira De Biofísica ... [et Al.]
dc.relationBraz. J. Med. Biol. Res.
dc.rightsaberto
dc.rights
dc.sourcePubMed
dc.subjectAnimals
dc.subjectCell Differentiation
dc.subjectCpg Islands
dc.subjectDna Methylation
dc.subjectEpigenesis, Genetic
dc.subjectGene Expression Regulation
dc.subjectGene Silencing
dc.subjectHumans
dc.subjectInheritance Patterns
dc.subjectMemory
dc.subjectNeoplasms
dc.titleThe Prima Donna Of Epigenetics: The Regulation Of Gene Expression By Dna Methylation.
dc.typeArtículos de revistas


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