Artículos de revistas
Enantioselective Syntheses Of (r)- And (s)-argentilactone And Their Cytotoxic Activities Against Cancer Cell Lines.
Registro en:
Bioorganic & Medicinal Chemistry. v. 12, n. 20, p. 5437-42, 2004-Oct.
0968-0896
10.1016/j.bmc.2004.07.044
15388170
Autor
de Fatima, Angelo
Kohn, Luciana Konecny
Antônio, Márcia Aparecida
de Carvalho, João Ernesto
Pilli, Ronaldo Aloise
Institución
Resumen
Concise total syntheses of (R)- and (S)-argentilactone have been developed via enantioselective catalytic allylation (ECA) and ring-closing metathesis pathways (four steps, 39% overall yield and 82-84% ee) from 2-octynal and their in vitro activity against cancer cells is described. 12 5437-42