Artículos de revistas
Stress-induced Desensitization Of The Cardiovascular Response To Noradrenaline In Unanesthetized Rats.
Registro en:
Brazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas / Sociedade Brasileira De Biofísica ... [et Al.]. v. 23, n. 10, p. 1041-4, 1990.
0100-879X
2101054
Autor
Martins, M C
Spadari, R C
Institución
Resumen
The present study was undertaken in order to analyse the effect of swimming stress on the blood pressure response to noradrenaline (NA) in unanesthetized rats. Swimming induced a desensitization of the blood pressure response to NA which was not blocked by previous animal treatment with prazosin (0.1 mg/kg). However, rats submitted to stress showed increased sensitivity to the prazosin blocking effect. The results suggest that swimming-induced desensitization of the cardiovascular response to NA is mediated by alpha rather than beta-1 adrenoceptors. 23 1041-4