Artículos de revistas
BIOGENIC SILVER NANOPARTICLES AND ITS ANTIFUNGAL ACTIVITY AS A NEW TOPICAL TRANSUNGUAL DRUG
Registro en:
Journal Of Nano Research. Trans Tech Publications Ltd, v. 20, n. 99, n. 107, 2012.
1662-5250
WOS:000313760400011
10.4028/www.scientific.net/JNanoR.20.99
Autor
Marcato, PD
Duran, M
Huber, S
Rai, M
Melo, PS
Alves, OL
Duran, N
Institución
Resumen
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Silver nanoparticles production was monitored by UV Vis and TEM micrograph and they were obtained as spherical and homogenous nanoparticles with a size of similar to 100 nm by photon correlation spectroscopy (PCS). Silver nanoparticles, in an IC80 range of 1-2 mu g/mL, showed significant antifungal activity against T. rubrum. Cytotoxicity through hemolytic activity against erythrocytes and the viability of V79 fibroblast or HL60 cells showed less toxicity than amphotericin B. The disk diffusion test showed that the silver nanoparticles exerted a similar inhibition zone that amphotericin B by a synergistic effect when added at the same time against T. rubrum culture. 20 99 107 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Brazilian Network of nanocosmetics Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)