A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax

dc.creatorRussell, B
dc.creatorSuwanarusk, R
dc.creatorBorlon, C
dc.creatorCosta, FTM
dc.creatorChu, CS
dc.creatorRijken, MJ
dc.creatorSriprawat, K
dc.creatorWarter, L
dc.creatorKoh, EGL
dc.creatorMalleret, B
dc.creatorColin, Y
dc.creatorBertrand, O
dc.creatorAdams, JH
dc.creatorD'Alessandro, U
dc.creatorSnounou, G
dc.creatorNosten, F
dc.creatorRenia, L
dc.date2011
dc.dateSEP 29
dc.date2014-07-30T13:42:44Z
dc.date2015-11-26T18:06:06Z
dc.date2014-07-30T13:42:44Z
dc.date2015-11-26T18:06:06Z
dc.date.accessioned2018-03-29T00:48:19Z
dc.date.available2018-03-29T00:48:19Z
dc.identifierBlood. Amer Soc Hematology, v. 118, n. 13, n. E74, n. E81, 2011.
dc.identifier0006-4971
dc.identifierWOS:000295359300002
dc.identifier10.1182/blood-2011-04-348748
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/53691
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/53691
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1293279
dc.descriptionCurrently, there are no reliable RBC invasion assays to guide the discovery of vaccines against Plasmodium vivax, the most prevalent malaria parasite in Asia and South America. Here we describe a protocol for an ex vivo P vivax invasion assay that can be easily deployed in laboratories located in endemic countries. The assay is based on mixing enriched cord blood reticulocytes with matured, trypsin-treated P vivax schizonts concentrated from clinical isolates. The reliability of this assay was demonstrated using a large panel of P vivax isolates freshly collected from patients in Thailand. (Blood. 2011;118(13):e74-e81)
dc.description118
dc.description13
dc.descriptionE74
dc.descriptionE81
dc.descriptionWellcome Trust of Great Britain, as part of Wellcome Trust-Mahidol University
dc.descriptionAgency for Science Technology and Research (A*STAR
dc.descriptionSingapore)
dc.descriptionWellcome Trust (United Kingdom)
dc.descriptionITM
dc.languageen
dc.publisherAmer Soc Hematology
dc.publisherWashington
dc.publisherEUA
dc.relationBlood
dc.relationBlood
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectDuffy-binding-protein
dc.subjectInfected Erythrocytes
dc.subjectBlood-group
dc.subjectInhibitory Antibodies
dc.subjectMonoclonal-antibody
dc.subjectLigand Domain
dc.subjectMalaria
dc.subjectSusceptibility
dc.subjectResistance
dc.subjectRosettes
dc.titleA reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax
dc.typeArtículos de revistas


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