Artículos de revistas
Synthesis of potentially bioactive PABA-related N-(aminoalkyl)lactamic amino acids and esters via selective SNAr reactions
Registro en:
Amino Acids. Springer, v. 40, n. 1, n. 197, n. 204, 2011.
0939-4451
WOS:000285781000018
10.1007/s00726-010-0634-z
Autor
Goncalves, RS
Abdelnur, PV
Santos, VG
Simas, RC
Eberlin, MN
Magalhaes, A
Gonzalez, ERP
Institución
Resumen
Potentially bioactive N-(aminoalkyl)lactamic amino acids and esters were synthesized in satisfactory to good yields by SNAr reactions of aromatic acids with N-(3-aminopropyl)lactams followed by esterification with tertiary amino alcohols. The addition-elimination SNAr mechanism was confirmed by NMR and MS measurements. 40 1 197 204