Brasil
| Artículos de revistas
Studies of the Deracemization of (+/-)-2-hydroxy-1-tetralone by Trichosporon cutaneum
Registro en:
Advanced Synthesis & Catalysis. Wiley-v C H Verlag Gmbh, v. 349, n. 6, n. 925, n. 932, 2007.
1615-4150
WOS:000246040000022
10.1002/adsc.200600331
Autor
Lunardi, I
Cazetta, T
Conceicao, GJA
Moran, PJS
Rodrigues, JAR
Institución
Resumen
The diastereo- and enantioselective bioreduction of (+/-)-2-hydroxy-1-tetralone (6) to the corresponding enantiopure (1S,2R)-cis-1,2-dihydroxy-1,2,3,4-tetrahydronaphthalene (1) (83 % isolated yield, > 99 % ee), mediated by resting cells of the yeast Trichosporon cutaneum CCT 1903 through dynamic kinetic resolution is reported. Deracemization of (+/-)-6 was observed in kinetic studies on the biotransformation of the enantiomers (R)-6 and (S)-6. 349 6 925 932