Objective: To compare the risk of accidents in patients with uncontrolled seizures, in seizure-free patients, and inpatients with chronic headache. Method: This was a prospective longitudinal case-controlled study with interviews. A semi-structured questionnaire was used in the epilepsy and headache outpatient clinics of the Hospital das Clinicas of UNICAMP. Results: Group I was composed of 48 patients with uncontrolled seizures, group II was composed of 24 seizure-free patients and group III was composed of 32 patients with headache. Thirty-nine patients (81%) in group 1, 13 (54%) in group II, and 19 (59%) in group III reported accidents in the last two years. In the first group, 649 accidents (89%) were related to epileptic seizures and the average number of accidents not related to seizures was 1.7. The average number of accidents in groups II and III were both2.4. Conclusion: Epileptic seizure was the most important factor determining the occurrence of accidents in people with epilepsy.662A175178