Incidence and antimicrobial susceptibility of Porphyromonas gingivalis isolated from mixed endodontic infections

dc.creatorJacinto, RC
dc.creatorGomes, BPFA
dc.creatorShah, HN
dc.creatorFerraz, CC
dc.creatorZaia, AA
dc.creatorSouza, FJ
dc.date2006
dc.dateJAN
dc.date2014-11-19T00:09:50Z
dc.date2015-11-26T17:55:03Z
dc.date2014-11-19T00:09:50Z
dc.date2015-11-26T17:55:03Z
dc.date.accessioned2018-03-29T00:38:48Z
dc.date.available2018-03-29T00:38:48Z
dc.identifierInternational Endodontic Journal. Blackwell Publishing, v. 39, n. 1, n. 62, n. 70, 2006.
dc.identifier0143-2885
dc.identifierWOS:000234403600010
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/59959
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/59959
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/59959
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1290932
dc.descriptionAim To investigate the prevalence of Porphyromonas gingivalis in root canals of infected teeth with periapical abscesses and to investigate the antimicrobial susceptibility of this species to some frequently prescribed antibiotics. Methodology Samples were obtained from 70 root canals of abscessed teeth. Microbial sampling, isolation and bacterial identification were accomplished using appropriate culture methods for anaerobic species. The antimicrobial susceptibility of the 20 strains of P. gingivalis isolated was determined by using the E-test. The antimicrobial agents tested were amoxicillin, amoxicillin + clavulanate, azythromycin, benzylpenicillin, cephaclor, clindamycin, erythromycin, metronidazole and tetracycline. Results A total of 352 individual strains, belonging to 69 different species, were isolated. Eighty three percent of the strains were strict anaerobes and 47.5% of the isolated bacteria were Gram-negative. Porphyromonas gingivalis was found in 20 root canals and was most frequently found in symptomatic cases. Statistically, the presence of P. gingivalis was related to purulent exudates and pain on palpation (both P < 0.05). All P. gingivalis strains were sensitive to amoxicillin, amoxicillin + clavulanate, cephaclor, clindamycin, benzylpenicyllin, metronidazole and tetracycline. The lowest range of minimum inhibitory concentration (MIC) (0.026-0.125 mu g mL(-1)) was observed against amoxicillin + clavulanate and clindamycin. The lowest MIC 90 was observed against clindamycin (0.064 mu g mL(-1)). One strain was resistant to erythromycin and eight strains were resistant to azythromycin. Conclusion Porphyromonas gingivalis pathogen is isolated with frequency from root canals of infected teeth with periapical abscesses. Amoxicillin, as well as amoxicillin-clavulanic acid and benzylpenicillin were effective against P. gingivalis.
dc.description39
dc.description1
dc.description62
dc.description70
dc.languageen
dc.publisherBlackwell Publishing
dc.publisherOxford
dc.publisherInglaterra
dc.relationInternational Endodontic Journal
dc.relationInt. Endod. J.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectanaerobic bacteria
dc.subjectantibiotics
dc.subjectantimicrobial susceptibility
dc.subjectendodontic infection
dc.subjectPorphyromonas gingivalis
dc.subjectBlack-pigmented Bacteroides
dc.subjectAdvanced Periodontitis Patients
dc.subjectGram-negative Anaerobes
dc.subjectRoot-canal Infections
dc.subjectSuccess Rate
dc.subjectBacteria
dc.subjectFusobacterium
dc.subjectAssociation
dc.subjectPathogens
dc.subjectAmoxicillin
dc.titleIncidence and antimicrobial susceptibility of Porphyromonas gingivalis isolated from mixed endodontic infections
dc.typeArtículos de revistas


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