Artículos de revistas
Association of exfoliation syndrome and central retinal vein occlusion: an ultrastructural analysis
Registro en:
Acta Ophthalmologica. Wiley-blackwell Publishing, Inc, v. 88, n. 1, n. 91, n. 95, 2010.
1755-375X
WOS:000274168900017
10.1111/j.1755-3768.2009.01578.x
Autor
Ritch, R
Prata, TS
de Moraes, CGV
Vessani, RM
Costa, VP
Konstas, AGP
Liebmann, JM
Schlotzer-Schrehardt, U
Institución
Resumen
Purpose: To evaluate prospectively the frequency with which exfoliation syndrome (XFS) occurs in patients with central retinal vein occlusion (CRVO) by clinical examination and ultrastructural examination of conjunctival biopsy specimens. Methods: Prospective observational case series. Thirty-six eyes of 36 consecutive patients with CRVO were investigated for XFS by slit-lamp examination and conjunctival biopsy when XFS was not clinically visible on examination. Results: A clinical diagnosis of XFS or a positive biopsy result for exfoliation material (XFM) was present in 22 of the 36 patients (61%; 95% confidence interval 45-75%). Twelve of these 22 patients (54%) had a clinical diagnosis of XFS. Aggregates of XFM were identified ultrastructurally in the biopsy specimens in 10 of 24 patients with no clinical signs of XFS (42%). Patients with and without XFS had similar distribution of age, gender, race and prevalence of systemic disorders. Twelve of the 22 (54%) XFS patients had neither glaucoma nor ocular hypertension prior to the CRVO. Conclusion: In accordance with previous retrospective and histological studies, this prospective, in vivo study suggests that CRVO is commonly associated with XFS. 88 1 91 95 New York Glaucoma Research Institute, New York City Deutsche Forschungsgemeinschaft [SFB 539] Deutsche Forschungsgemeinschaft [SFB 539]